2,5-Difluorobenzenesulfonyl chloride → N-{3-[5-(2-Chloro-4-pyrimidinyl)-2-(4-morpholinyl)-1,3-thiazol-4-yl]-2,4-difluorophenyl}-2,5-difluorobenzenesulfonamide

반응식

[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:19]3[c:20]([F:27])[c:21]([NH2:22])[cH:23][cH:24][c:25]3[F:26])[n:10][c:11]([N:13]3[CH2:14][CH2:15][O:16][CH2:17][CH2:18]3)[s:12]2)[n:7]1.[F:28][c:29]1[c:30]([S:36](=[O:37])(=[O:38])[Cl:39])[cH:31][c:32]([F:35])[cH:33][cH:34]1>>[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:19]3[c:20]([F:27])[c:21]([NH:22][S:36]([c:30]4[c:29]([F:28])[cH:34][cH:33][c:32]([F:35])[cH:31]4)(=[O:37])=[O:38])[cH:23][cH:24][c:25]3[F:26])[n:10][c:11]([N:13]3[CH2:14][CH2:15][O:16][CH2:17][CH2:18]3)[s:12]2)[n:7]1

참가 물질

반응물 2

HCID 27369112,5-Difluorobenzenesulfonyl chloride

HCID 57989700HCID 57989700, 화합물

생성물 1

HCID 57989715N-{3-[5-(2-Chloro-4-pyrimidinyl)-2-(4-morpholinyl)-1,3-thiazol-4-yl]-2,4-difluorophenyl}-2,5-difluorobenzenesulfonamide

출처 및 근거

ORD 기록: ord-482fafaa79134790b0b0608a29b3048d
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

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