4-bromo-1H-pyrazolo[4,3-c]pyridin-3-amine → N-(2-{3-[4-(3-amino-1H-pyrazolo[4,3-c]pyrid-4-yl)phenyl]ureido}-4-trifluoromethylphenyl)acetamide

반응식

[Br:1][c:2]1[n:3][cH:4][cH:5][c:6]2[c:7]1[c:8]([NH2:11])[n:9][nH:10]2.[CH3:12][C:13]1([CH3:14])[C:15]([CH3:16])([CH3:17])[O:18][B:19]([c:20]2[cH:21][cH:22][c:23]([NH:26][C:27]([NH:28][c:29]3[c:30]([NH:39][C:40]([CH3:41])=[O:42])[cH:31][cH:32][c:33]([C:35]([F:36])([F:37])[F:38])[cH:34]3)=[O:43])[cH:24][cH:25]2)[O:44]1>>[c:2]1(-[c:20]2[cH:21][cH:22][c:23]([NH:26][C:27]([NH:28][c:29]3[c:30]([NH:39][C:40]([CH3:41])=[O:42])[cH:31][cH:32][c:33]([C:35]([F:36])([F:37])[F:38])[cH:34]3)=[O:43])[cH:24][cH:25]2)[n:3][cH:4][cH:5][c:6]2[c:7]1[c:8]([NH2:11])[n:9][nH:10]2

참가 물질

반응물 2

HCID 583807624-bromo-1H-pyrazolo[4,3-c]pyridin-3-amine

HCID 67329019N-(2-{3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ureido}-4-trifluoromethylphenyl)acetamide

생성물 1

HCID 24897406N-(2-{3-[4-(3-amino-1H-pyrazolo[4,3-c]pyrid-4-yl)phenyl]ureido}-4-trifluoromethylphenyl)acetamide

출처 및 근거

ORD 기록: ord-77cc69d1d55040389573acee5083759a
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

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