Tetrahydrofuran → 4-[(1-benzenesulfonyl-5-fluoro-1H-indol-2-yl)-hydroxy-methyl]4-propyl-piperidine-1-carboxylic acid tert-butyl ester

HRID 682389노트

반응식

[C:20]([Li:21])([CH3:22])([CH3:23])[CH3:24].[C:25]([CH3:26])([CH3:27])([CH3:28])[O:29][C:30](=[O:31])[N:32]1[CH2:33][CH2:34][C:35]([CH2:38][CH2:39][CH3:40])([CH:41]=[O:42])[CH2:36][CH2:37]1.[CH2:43]1[O:44][CH2:45][CH2:46][CH2:47]1.[c:1]1([S:7](=[O:8])(=[O:9])[n:10]2[cH:11][cH:12][c:13]3[cH:14][c:15]([F:19])[cH:16][cH:17][c:18]23)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([S:7](=[O:8])(=[O:9])[n:10]2[c:11]([CH:41]([C:35]3([CH2:38][CH2:39][CH3:40])[CH2:34][CH2:33][N:32]([C:30]([O:29][C:25]([CH3:26])([CH3:27])[CH3:28])=[O:31])[CH2:37][CH2:36]3)[OH:42])[cH:12][c:13]3[cH:14][c:15]([F:19])[cH:16][cH:17][c:18]23)[cH:2][cH:3][cH:4][cH:5][cH:6]1