4-Benzyloxyaniline → 4-(4-Benzyloxyanilino)6-chloropyrido[3,4-d]pyrimidine

HRID 6828

반응식

HRID 6828 반응식
[CH2:1]([O:8][C:9]1[CH:15]=[CH:14][C:12]([NH2:13])=[CH:11][CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl[C:17]1[C:18]2[CH:26]=[C:25]([Cl:27])[N:24]=[CH:23][C:19]=2[N:20]=[CH:21][N:22]=1>>[CH2:1]([O:8][C:9]1[CH:10]=[CH:11][C:12]([NH:13][C:17]2[C:18]3[CH:26]=[C:25]([Cl:27])[N:24]=[CH:23][C:19]=3[N:20]=[CH:21][N:22]=2)=[CH:14][CH:15]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

참가 물질

3

반응물 2

HCID 228604-BenzyloxyanilineHCID 108218764,6-Dichloropyrido[3,4-d]pyrimidine

생성물 1

HCID 219521684-(4-Benzyloxyanilino)6-chloropyrido[3,4-d]pyrimidine

실험 절차

Prepared according to Procedure A from 4-benzyloxyaniline (1 eq) and 4,6-dichloro-pyrido[3,4-d]pyrimidine (1 eq); δH (CDCl3) 9.11 (1H, s), 8.78 (1H, s), 7.75 (1H, d), 7.56 (2H, dd), 7.40 (5H, m), 7.15 (2H, d), 5.10 (2H, s); m/z (M+1)+409.

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-5fb41e082e254b2c9a8820aac25dfc35
출처 데이터셋
uspto-grants-2006_08
특허 번호
US07084147B2

연결된 노트

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