Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4,6-Dichloropyrido[3,4-d]pyrimidine → (6-Chloropyrido[3,4-d]pyrimidin-4-yl)-(4-(3-fluorobenzyloxy)-phenyl)-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4,6-Dichloropyrido[3,4-d]pyrimidine | HCID 10821876 | — |
| 반응물 | 4-(3-Fluoro-benzyloxy)-phenylamine | HCID 16775314 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | (6-Chloropyrido[3,4-d]pyrimidin-4-yl)-(4-(3-fluorobenzyloxy)-phenyl)-amine | HCID 21952062 | — |
반응 단계
4,6-Dichloro-pyrido[3,4-d]pyrimidine (1 g) and 4-(3-fluorobenzyloxy)aniline (1.08 g) in acetonitrile (70 ml) were reacted together as in Procedure A. The product was collected by filtration as a yellow solid (1.86 g); m/z 381 (M+1)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07084147B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-8b3bea1d833140cf9b8c1582932f75e3 |
| 출처 메모 | uspto-grants-2006_08 |