2-Pyridinecarboxylicacid,5-(2,2,3,3-tetrafluoropropoxy)- → N-[3-(2-amino-5,5-difluoro-4,6,6-trimethyl-1,3-oxazin-4-yl)-4-fluorophenyl]-5-(2,2,3,3-tetrafluoropropoxy)pyridine-2-carboxamide

반응식

[F:21][C:22]([CH2:23][O:24][c:25]1[cH:26][cH:27][c:28]([C:31](=[O:32])[OH:33])[n:29][cH:30]1)([CH:34]([F:35])[F:36])[F:37].[NH2:1][c:2]1[cH:3][cH:4][c:5]([F:20])[c:6]([C:8]2([CH3:19])[N:9]=[C:10]([NH2:18])[O:11][C:12]([CH3:16])([CH3:17])[C:13]2([F:14])[F:15])[cH:7]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([F:20])[c:6]([C:8]2([CH3:19])[N:9]=[C:10]([NH2:18])[O:11][C:12]([CH3:16])([CH3:17])[C:13]2([F:14])[F:15])[cH:7]1)[C:31]([c:28]1[cH:27][cH:26][c:25]([O:24][CH2:23][C:22]([F:21])([CH:34]([F:35])[F:36])[F:37])[cH:30][n:29]1)=[O:32]

참가 물질

반응물 2

HCID 574758552-Pyridinecarboxylicacid,5-(2,2,3,3-tetrafluoropropoxy)-

HCID 672341894-(5-Amino-2-fluorophenyl)-5,5-difluoro-4,6,6-trimethyl-1,3-oxazin-2-amine

생성물 1

HCID 75986893N-[3-(2-amino-5,5-difluoro-4,6,6-trimethyl-1,3-oxazin-4-yl)-4-fluorophenyl]-5-(2,2,3,3-tetrafluoropropoxy)pyridine-2-carboxamide

출처 및 근거

ORD 기록: ord-e5d236dba41644319e251b58d19d77c4
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

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