Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → Tert-butyl 2-(2-bromo-4-formylphenoxy)acetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 3-Bromo-4-hydroxybenzaldehyde | HCID 76308 | — |
| 반응물 | tert-Butyl bromoacetate | HCID 79177 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | Tert-butyl 2-(2-bromo-4-formylphenoxy)acetate | HCID 17999215 | 951.9% |
반응 단계
To a solution of 3-bromo-4-hydroxybenzaldehyde (100 g, 50 mol, 1 eq) in acetone (500 mL) was added potassium carbonate (135 g, 100 mmol, 2 eq) followed by t-butyl 2-bromoacetate (100 g, 50 mmol, 1 eq). After stirring at room temperature for 2 h, the acetone was removed in vacuo and the resultant residue was washed with water to give 150 g (89%) of t-butyl 2-(2-bromo-4-formylphenoxy)acetate (1).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08822467B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-53c9217a3475467587c1b302503c9848 |
| 출처 메모 | uspto-grants-2014_09 |