8-Bromo-1-(1,3-dimethyl-1H-pyrazol-4-yl)-3-methyl-1,3-dihydro-imidazo[4,5-c]quinolin-2-one → 8-bromo-3-methyl-1-{3-methyl-1-[2-(4-methyl-piperazin-1-yl)-2-oxo-ethyl]-1H-pyrazol-4-yl}-1,3-dihydro-imidazo[4,5-c]quinolin-2-one

반응식

[Br:1][c:2]1[cH:3][c:4]2[c:5]3[c:6]([cH:7][n:8][c:9]2[cH:10][cH:11]1)[n:12]([CH3:23])[c:13](=[O:22])[n:14]3-[c:15]1[c:16]([CH3:21])[n:17][n:18]([CH3:20])[cH:19]1.[Br:24][c:25]1[cH:26][cH:27][c:28]2[n:29][cH:30][c:31]3[nH:32][c:33](=[O:34])[n:35](-[c:36]4[c:37]([CH3:38])[n:39][n:40]([CH2:41][C:44](=[O:45])[N:46]5[CH2:47][CH2:48][N:49]([CH3:52])[CH2:50][CH2:51]5)[cH:42]4)[c:43]3[c:53]2[cH:54]1>>[Br:1][c:2]1[cH:3][c:4]2[c:5]3[c:6]([cH:7][n:8][c:9]2[cH:10][cH:11]1)[n:12]([CH3:23])[c:13](=[O:22])[n:14]3-[c:15]1[c:16]([CH3:21])[n:17][n:18]([CH2:20][C:44](=[O:45])[N:46]2[CH2:47][CH2:48][N:49]([CH3:52])[CH2:50][CH2:51]2)[cH:19]1