Thionyl Chloride → 4-(4-Methyl-oxazol-5-yl)-benzoyl chloride

HRID 68762노트

반응식

HRID 68762 반응식
S(Cl)([Cl:3])=O.[CH3:5][C:6]1[N:7]=[CH:8][O:9][C:10]=1[C:11]1[CH:19]=[CH:18][C:14]([C:15](O)=[O:16])=[CH:13][CH:12]=1>ClCCl>[CH3:5][C:6]1[N:7]=[CH:8][O:9][C:10]=1[C:11]1[CH:19]=[CH:18][C:14]([C:15]([Cl:3])=[O:16])=[CH:13][CH:12]=1

참가 물질

4

반응물 2

HCID 24386Thionyl ChlorideHCID 682900554-(4-Methyloxazol-5-yl)benzoic acid

생성물 1

HCID 866782114-(4-Methyl-oxazol-5-yl)-benzoyl chloride

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

Thionyl chloride (2.00 mL) is added to 4-(4-methyl-oxazol-5-yl)-benzoic acid (400 mg) in dichloromethane (5 mL) and the mixture is stirred for two days at room temperature. The solvent is evaporated to give the title compound, which is used without further purification for the next reaction step.

후처리

  1. customThe solvent is evaporated

출처 및 근거

ORD 기록
ord-00937668ffff45a6bfe0b720f329e30d
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08822471B2

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