Cyclopropylamine → N-cyclopropyl-1-(5-ethylpyrazin-2-yl)piperidin-4-amine
반응식
[CH2:1]([C:3]1[N:4]=[CH:5][C:6]([N:9]2[CH2:14][CH2:13][C:12](=O)[CH2:11][CH2:10]2)=[N:7][CH:8]=1)[CH3:2].[CH:16]1([NH2:19])[CH2:18][CH2:17]1>>[CH:16]1([NH:19][CH:12]2[CH2:13][CH2:14][N:9]([C:6]3[CH:5]=[N:4][C:3]([CH2:1][CH3:2])=[CH:8][N:7]=3)[CH2:10][CH2:11]2)[CH2:18][CH2:17]1참가 물질
3
실험 절차
The title compound is prepared from 1-(5-ethyl-pyrazin-2-yl)-piperidin-4-one and cyclopropylamine following a procedure analogous to that described in Intermediate 7. LC (method 1): tR=0.65 min; Mass spectrum (ESI+): m/z=247 [M+H]+.
출처 및 근거
- ORD 기록
- ord-e4de340d33be44bf8664358b3abed589
- 출처 데이터셋
- uspto-grants-2014_09
- 특허 번호
- US08822471B2
반응 노트
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