Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-Bromo-1,3-difluoro-2-iodobenzene → 5-(4-Bromo-2,6-difluorophenyl)oxazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-Bromo-1,3-difluoro-2-iodobenzene | HCID 2782702 | — |
| 반응물 | 5-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(tris(propan-2-yl)silyl)-1,3-oxazole | HCID 44224311 | — |
| 생성물 | 5-(4-Bromo-2,6-difluorophenyl)oxazole | HCID 68289564 | — |
반응 단계
The title compound is prepared from 5-bromo-1,3-difluoro-2-iodo-benzene and 5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-2-triisopropylsilanyl-oxazole following a procedure analogous to that described in Intermediate 27. LC (method 1): tR=1.18 min; Mass spectrum (ESI+): m/z=260 [M+H]+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08822471B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-60bf5a2ea0b34182be7b171335a2a86c |
| 출처 메모 | uspto-grants-2014_09 |