2-Chloro-5-ethylpyrimidine → HCID 68290585, 화합물

HRID 68799

반응식

HRID 68799 반응식
C(OC(=O)[N:7]([CH:15]1[CH2:17][CH2:16]1)[C@@H:8]1[CH2:13][CH2:12][NH:11][CH2:10][C@@H:9]1[F:14])(C)(C)C.Cl[C:20]1[N:25]=[CH:24][C:23]([CH2:26][CH3:27])=[CH:22][N:21]=1>>[CH:15]1([NH:7][C@@H:8]2[CH2:13][CH2:12][N:11]([C:20]3[N:25]=[CH:24][C:23]([CH2:26][CH3:27])=[CH:22][N:21]=3)[CH2:10][C@@H:9]2[F:14])[CH2:16][CH2:17]1

참가 물질

3

반응물 2

HCID 35727632-Chloro-5-ethylpyrimidineHCID 68290240tert-butyl N-cyclopropyl-N-[(3S,4R)-3-fluoropiperidin-4-yl]carbamate

생성물 1

HCID 68290585HCID 68290585, 화합물

실험 절차

The title compound is prepared from cyclopropyl-[(3S,4R)-3-fluoro-piperidin-4-yl]-carbamic acid tert-butyl ester and 2-chloro-5-ethyl-pyrimidine following a procedure analogous to that described for Intermediate 73.

출처 및 근거

ORD 기록
ord-745d09c422304fef8253d0e66e6306c1
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08822471B2

연결된 노트

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