2-Chloro-5-methoxypyrimidine → HCID 68290594, 화합물

HRID 68826노트

반응식

HRID 68826 반응식
[CH:1]1([N:4]([CH:18]2[CH2:23][CH2:22][NH:21][CH2:20][CH2:19]2)[C:5](=[O:17])[C:6]2[CH:11]=[CH:10][C:9]([C:12]3[O:16][CH:15]=[N:14][CH:13]=3)=[CH:8][CH:7]=2)[CH2:3][CH2:2]1.Cl[C:25]1[N:30]=[CH:29][C:28]([O:31][CH3:32])=[CH:27][N:26]=1>>[CH:1]1([N:4]([CH:18]2[CH2:23][CH2:22][N:21]([C:25]3[N:30]=[CH:29][C:28]([O:31][CH3:32])=[CH:27][N:26]=3)[CH2:20][CH2:19]2)[C:5](=[O:17])[C:6]2[CH:7]=[CH:8][C:9]([C:12]3[O:16][CH:15]=[N:14][CH:13]=3)=[CH:10][CH:11]=2)[CH2:3][CH2:2]1

참가 물질

3

반응물 2

HCID 5890582-Chloro-5-methoxypyrimidineHCID 68289931N-Cyclopropyl-4-oxazol-5-yl-N-piperidin-4-yl-benzamide

생성물 1

HCID 68290594HCID 68290594, 화합물

실험 절차

The title compound is prepared from N-cyclopropyl-4-oxazol-5-yl-N-piperidin-4-yl-benzamide and 2-chloro-5-methoxy-pyrimidine following a procedure analogous to that described in Example 19. LC (method 9): tR=1.88 min; Mass spectrum (ESI+): m/z=420 [M+H]+.

출처 및 근거

ORD 기록
ord-45085be1a7cb46f28b9a6ad7350cd8f6
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08822471B2

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