HCID 68289566, 화합물 → N-[1-(3-tert-Butyl-[1,2,4]oxadiazol-5-yl)-piperidin-4-yl]-N-cyclopropyl-3-fluoro-4-oxazol-5-yl-benzamide

HRID 68862

반응식

HRID 68862 반응식
[C:1]([C:5]1[N:9]=[C:8]([N:10]2[CH2:15][CH2:14][CH:13]([NH:16][CH:17]3[CH2:19][CH2:18]3)[CH2:12][CH2:11]2)[O:7][N:6]=1)([CH3:4])([CH3:3])[CH3:2].[F:20][C:21]1[CH:22]=[C:23]([CH:27]=[CH:28][C:29]=1[C:30]1[O:34][CH:33]=[N:32][CH:31]=1)[C:24](O)=[O:25]>>[C:1]([C:5]1[N:9]=[C:8]([N:10]2[CH2:11][CH2:12][CH:13]([N:16]([CH:17]3[CH2:19][CH2:18]3)[C:24](=[O:25])[C:23]3[CH:27]=[CH:28][C:29]([C:30]4[O:34][CH:33]=[N:32][CH:31]=4)=[C:21]([F:20])[CH:22]=3)[CH2:14][CH2:15]2)[O:7][N:6]=1)([CH3:4])([CH3:2])[CH3:3]

참가 물질

3

반응물 2

HCID 68289566HCID 68289566, 화합물HCID 682901443-Fluoro-4-oxazol-5-yl-benzoic acid

생성물 1

HCID 68351901N-[1-(3-tert-Butyl-[1,2,4]oxadiazol-5-yl)-piperidin-4-yl]-N-cyclopropyl-3-fluoro-4-oxazol-5-yl-benzamide

실험 절차

The title compound is prepared from [1-(3-tert-butyl-[1,2,4]oxadiazol-5-yl)-piperidin-4-yl]-cyclopropyl-amine and 3-fluoro-4-oxazol-5-yl-benzoic acid following a procedure analogous to that described in Example 17. LC (method 1): tR=1.26 min; Mass spectrum (ESI+): m/z=454 [M+H]+.

출처 및 근거

ORD 기록
ord-72f6f3b0cba3499c8553271fcf34e465
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08822471B2

연결된 노트

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