HCID 68289603, 화합물 → N-Cyclopropyl-N-[1-(5-ethyl-pyrazin-2-yl)-piperidin-4-yl]-3-fluoro-4-oxazol-5-yl-benzamide

HRID 68863노트

반응식

HRID 68863 반응식
[CH:1]1([NH:4][CH:5]2[CH2:10][CH2:9][N:8]([C:11]3[CH:16]=[N:15][C:14]([CH2:17][CH3:18])=[CH:13][N:12]=3)[CH2:7][CH2:6]2)[CH2:3][CH2:2]1.[F:19][C:20]1[CH:21]=[C:22]([CH:26]=[CH:27][C:28]=1[C:29]1[O:33][CH:32]=[N:31][CH:30]=1)[C:23](O)=[O:24]>>[CH:1]1([N:4]([CH:5]2[CH2:10][CH2:9][N:8]([C:11]3[CH:16]=[N:15][C:14]([CH2:17][CH3:18])=[CH:13][N:12]=3)[CH2:7][CH2:6]2)[C:23](=[O:24])[C:22]2[CH:26]=[CH:27][C:28]([C:29]3[O:33][CH:32]=[N:31][CH:30]=3)=[C:20]([F:19])[CH:21]=2)[CH2:2][CH2:3]1

참가 물질

3

반응물 2

HCID 68289603HCID 68289603, 화합물HCID 682901443-Fluoro-4-oxazol-5-yl-benzoic acid

생성물 1

HCID 68290662N-Cyclopropyl-N-[1-(5-ethyl-pyrazin-2-yl)-piperidin-4-yl]-3-fluoro-4-oxazol-5-yl-benzamide

실험 절차

The title compound is prepared from cyclopropyl-[1-(5-ethyl-pyrazin-2-yl)-piperidin-4-yl]-amine and 3-fluoro-4-oxazol-5-yl-benzoic acid following a procedure analogous to that described in Example 17. LC (method 1): tR=1.18 min; Mass spectrum (ESI+): m/z=436 [M+H]+.

출처 및 근거

ORD 기록
ord-2252c2a5ced9446da25ca4aa2a9864e8
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08822471B2

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