PyBroP → N-Cyclopropyl-N-(3'-fluoro-5'-trifluoromethyl-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-yl)-4-(2-methyl-imidazol-1-yl)-benzamide

반응식

F[P-](F)(F)(F)(F)F.Br[P+](N1CCCC1)(N1CCCC1)N1CCCC1.[CH:25]1([NH:28][CH:29]2[CH2:34][CH2:33][N:32]([C:35]3[C:40]([F:41])=[CH:39][C:38]([C:42]([F:45])([F:44])[F:43])=[CH:37][N:36]=3)[CH2:31][CH2:30]2)[CH2:27][CH2:26]1.[CH3:46][C:47]1[N:48]([C:52]2[CH:60]=[CH:59][C:55]([C:56](O)=[O:57])=[CH:54][CH:53]=2)[CH:49]=[CH:50][N:51]=1.C(#N)C.O.FC(F)(F)C(O)=O>CN(C)C=O.C(N(CC)CC)C>[CH:25]1([N:28]([CH:29]2[CH2:34][CH2:33][N:32]([C:35]3[C:40]([F:41])=[CH:39][C:38]([C:42]([F:44])([F:43])[F:45])=[CH:37][N:36]=3)[CH2:31][CH2:30]2)[C:56](=[O:57])[C:55]2[CH:54]=[CH:53][C:52]([N:48]3[CH:49]=[CH:50][N:51]=[C:47]3[CH3:46])=[CH:60][CH:59]=2)[CH2:26][CH2:27]1