8-Amino-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one → 2-[5-Chloro-2-(2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-8-ylamino)-pyrimidin-4-ylamino]-3-fluoro-N-methyl-5-(1-methyl-1H-pyrazol-4-yl)-benzamide

HRID 689048

반응식

HRID 689048 반응식
[Cl:14][c:15]1[n:16][cH:17][c:18]([Cl:39])[c:19]([NH:21][c:22]2[c:23]([C:24](=[O:25])[NH:26][CH3:27])[cH:28][c:29](-[c:33]3[cH:34][n:35][n:36]([CH3:38])[cH:37]3)[cH:30][c:31]2[F:32])[n:20]1.[NH2:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:13]1)[NH:7][C:8](=[O:12])[CH2:9][CH2:10][CH2:11]2>>[NH:1]([c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:13]1)[NH:7][C:8](=[O:12])[CH2:9][CH2:10][CH2:11]2)[c:15]1[n:16][cH:17][c:18]([Cl:39])[c:19]([NH:21][c:22]2[c:23]([C:24](=[O:25])[NH:26][CH3:27])[cH:28][c:29](-[c:33]3[cH:34][n:35][n:36]([CH3:38])[cH:37]3)[cH:30][c:31]2[F:32])[n:20]1

참가 물질

3

반응물 2

HCID 46151688-Amino-1,3,4,5-tetrahydro-2H-1-benzazepin-2-oneHCID 866340362-(2,5-dichloro-pyrimidin-4-ylamino)-3-fluoro-N-methyl-5-(1-methyl-1H-pyrazol-4-yl)-benzamide

생성물 1

HCID 668304652-[5-Chloro-2-(2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-8-ylamino)-pyrimidin-4-ylamino]-3-fluoro-N-methyl-5-(1-methyl-1H-pyrazol-4-yl)-benzamide

출처 및 근거

ORD 기록
ord-34d5650478074b0a94c1554527ff561d
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

연결된 노트

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