Chlorotrimethylsilane → 6-(4-(1-methyl-1H-indazol-5-ylamino)-7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-2-ylamino)-3,4-dihydroquinolin-2(1H)-one

HRID 691707

반응식

HRID 691707 반응식
[CH3:44][Si:45]([Cl:46])([CH3:47])[CH3:48].[Cl:1][c:2]1[n:3][c:4]([NH:21][c:22]2[cH:23][c:24]3[cH:25][n:26][n:27]([CH3:31])[c:28]3[cH:29][cH:30]2)[c:5]2[c:6]([n:7]1)[n:8]([S:11](=[O:12])(=[O:13])[c:14]1[cH:15][cH:16][c:17]([CH3:18])[cH:19][cH:20]1)[cH:9][cH:10]2.[NH2:32][c:33]1[cH:34][c:35]2[c:40]([cH:41][cH:42]1)[NH:39][C:38](=[O:43])[CH2:37][CH2:36]2>>[c:2]1([NH:32][c:33]2[cH:34][c:35]3[c:40]([cH:41][cH:42]2)[NH:39][C:38](=[O:43])[CH2:37][CH2:36]3)[n:3][c:4]([NH:21][c:22]2[cH:23][c:24]3[cH:25][n:26][n:27]([CH3:31])[c:28]3[cH:29][cH:30]2)[c:5]2[c:6]([n:7]1)[n:8]([S:11](=[O:12])(=[O:13])[c:14]1[cH:15][cH:16][c:17]([CH3:18])[cH:19][cH:20]1)[cH:9][cH:10]2

참가 물질

4

반응물 3

HCID 6397ChlorotrimethylsilaneHCID 49127596-amino-3,4-dihydroquinolin-2(1H)-oneHCID 866280432-chloro-N-(1-methyl-1H-indazol-5-yl)-7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

생성물 1

HCID 685793896-(4-(1-methyl-1H-indazol-5-ylamino)-7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-2-ylamino)-3,4-dihydroquinolin-2(1H)-one

출처 및 근거

ORD 기록
ord-3cd2085af0084c43ae116297839777b1
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

연결된 노트

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