5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo(2,3-b)pyridine → N-(3-(7-morpholino-5-(1H-pyrrolo[2,3-b]pyridin-5-yl)thiazolo[5,4-d]pyrimidin-2-yl)benzyl)methanesulfonamide

반응식

[CH3:29][C:30]1([CH3:31])[C:32]([CH3:33])([CH3:34])[O:35][B:36]([c:37]2[cH:38][c:39]3[c:40]([n:41][cH:42]2)[nH:43][cH:44][cH:45]3)[O:46]1.[Cl:1][c:2]1[n:3][c:4]([N:23]2[CH2:24][CH2:25][O:26][CH2:27][CH2:28]2)[c:5]2[c:6]([n:7]1)[s:8][c:9](-[c:11]1[cH:12][c:13]([CH2:14][NH:15][S:16](=[O:17])(=[O:18])[CH3:19])[cH:20][cH:21][cH:22]1)[n:10]2>>[c:2]1(-[c:37]2[cH:38][c:39]3[c:40]([n:41][cH:42]2)[nH:43][cH:44][cH:45]3)[n:3][c:4]([N:23]2[CH2:24][CH2:25][O:26][CH2:27][CH2:28]2)[c:5]2[c:6]([n:7]1)[s:8][c:9](-[c:11]1[cH:12][c:13]([CH2:14][NH:15][S:16](=[O:17])(=[O:18])[CH3:19])[cH:20][cH:21][cH:22]1)[n:10]2

참가 물질

반응물 2

HCID 242087895-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo(2,3-b)pyridine

HCID 86630071HCID 86630071, 화합물

생성물 1

HCID 25254300N-(3-(7-morpholino-5-(1H-pyrrolo[2,3-b]pyridin-5-yl)thiazolo[5,4-d]pyrimidin-2-yl)benzyl)methanesulfonamide

출처 및 근거

ORD 기록: ord-c8c6c97ae5f0490984b98537e4cb2289
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

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