Hydrogen chloride-ethyl acetate → 4-Methoxybutyric acid hydrazide hydrochloride salt

HRID 6925

반응식

HRID 6925 반응식
[CH3:1][O:2][CH2:3][CH2:4][CH2:5][C:6]([NH:8][NH2:9])=[O:7].[ClH:10].C(OCC)(=O)C>C(OCC)(=O)C>[ClH:10].[CH3:1][O:2][CH2:3][CH2:4][CH2:5][C:6]([NH:8][NH2:9])=[O:7]

참가 물질

4

반응물 2

HCID 21866389Hydrogen chloride-ethyl acetateHCID 30031554N'-(4-Methoxybutyryl)hydrazine

생성물 1

HCID 865902274-Methoxybutyric acid hydrazide hydrochloride salt수율 89%

시약·촉매·용매 1

HCID 8857Ethyl Acetate용매

실험 절차

N′-(4-Methoxybutyryl)hydrazine carboxylic acd tert-butyl ester (9.30 g) was dissolved in ethyl acetate (50 ml), followed by addition of 4 mol/liter hydrochloric acid/ethyl acetate solution (150 ml), and stirred at ambient temperature for 2 hours. After the reaction solution was concentrated under reduced pressure, the resulting residue was washed with n-hexane, to afford 4-methoxybutyric acid hydrazide hydrochloride salt as pale yellow solid (5.99 g, 89%). The physico-chemical values are as follows.

후처리

  1. concentrationAfter the reaction solution was concentrated under reduced pressure
  2. washthe resulting residue was washed with n-hexane

출처 및 근거

ORD 기록
ord-2f1fc4e63bcd49baab4faaaf5cb38cf8
출처 데이터셋
uspto-grants-2006_08
특허 번호
US07084164B2

연결된 노트

불러오는 중…