Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Fluorophenylboronic acid → HCID 57916946, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Fluorophenylboronic acid | HCID 285645 | — |
| 반응물 | Trifluoromethanesulfonic acid 2-[4-((R)-3-dimethylaminopyrrolidin-1-yl)-3-fluorophenyl]-1-oxo-1,2,3,4-tetrahydroisoquinolin-6-yl ester | HCID 86635103 | — |
| 생성물 | HCID 57916946 | HCID 57916946 | — |
반응 단계
Trifluoromethanesulfonic acid 2-[4-((R)-3-dimethylaminopyrrolidin-1-yl)-3-fluorophenyl]-1-oxo-1,2,3,4-tetrahydroisoquinolin-6-yl ester was reacted with 4-fluorophenylboronic acid by method O. The product with the molecular weight of 447.53 (C27H27F2N3O) was obtained in this way; MS (ESI): 448 (M+H+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08822495B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-5b3272e8745644018ae198ec46988c42 |
| 출처 메모 | uspto-grants-2014_09 |