(2S)-2-methylpyrrolidine → (3R)-3-(Pyrrolidin-1-YL)pyrrolidine

HRID 69428노트

반응식

HRID 69428 반응식
C[C@H]1CCCN1.C[C@H:8]1[CH2:12][CH2:11][CH2:10][N:9]1[C@H:13]1[CH2:17][CH2:16][NH:15][CH2:14]1>>[N:9]1([C@@H:13]2[CH2:17][CH2:16][NH:15][CH2:14]2)[CH2:10][CH2:11][CH2:12][CH2:8]1

참가 물질

3

반응물 2

HCID 6999702(2S)-2-methylpyrrolidineHCID 59401808(2S,3'S)-2-Methyl-[1,3]bipyrrolidinyl

생성물 1

HCID 7176272(3R)-3-(Pyrrolidin-1-YL)pyrrolidine

실험 절차

By use of (S)-2-methyl-pyrrolidine in the substitution reaction step (2S,3′S)-2-methyl-[1,3′]bipyrroldinyl is obtained.

후처리

  1. customis obtained

출처 및 근거

ORD 기록
ord-35de69568b0048cf9a90acdfb65dc08e
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08822495B2

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