Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Butanal → 1,1-Di-(7-azaindol-3-yl)-butane
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Butanal | HCID 261 | — |
| 반응물 | 1H-Pyrrolo(2,3-b)pyridine | HCID 9222 | — |
| 생성물 | 1,1-Di-(7-azaindol-3-yl)-butane | HCID 22019283 | 15% |
반응 단계
ST 1436 was prepared as described in example 2/2 from 7-azaindole and butyraldehyde. The reaction, however, was heated under reflux for 48 hours. The end product was isolated and purified chromatographically on a silica column eluting with a CH2Cl2:CH3COCH3 gradient ranging from 9:1 to 4:6. Yield 15%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07084166B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-7e699b14c36a4cb1ab9bfad78d80f704 |
| 출처 메모 | uspto-grants-2006_08 |