참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Acetic Anhydride | HCID 7918 | — |
| 반응물 | Lead diacetate | HCID 9317 | — |
| 반응물 | Sodium Carbonate | HCID 10340 | — |
| 반응물 | 5-[(R)-1-(tetrahydrofuran-2-yl)methoxy]-indan-1-one | HCID 68989306 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | HCID 68991904 | HCID 68991904 | — |
반응 단계
A mixture of 5-[(R)-1-(tetrahydrofuran-2-yl)methoxy]-indan-1-one (1.25 g), acetic anhydride (3 mL), lead acetate (3.58 g) and acetic acid (3 mL) was stirred for 48 h at 100° C. After adding sodium carbonate solution it was extracted with ether, dried over magnesium sulfate and concentrated. The residue was chromatographed on silica gel. In this way the product was obtained with molecular weight 290.32 (C16H18O5); MS (ESI): 291 (M+H+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08822495B2 |
|---|
| 출처 데이터셋 | uspto-grants-2014_09 |
|---|
| ORD ID | ord-c20828727c024484b3872a5e0f98f411 |
|---|
| 출처 메모 | uspto-grants-2014_09 |
|---|
