Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 5-[(R)-1-(tetrahydrofuran-2-yl)methoxy]-indan-1-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | 5-Hydroxy-1-indanone | HCID 233147 | — |
| 반응물 | HCID 18649742 | HCID 18649742 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 5-[(R)-1-(tetrahydrofuran-2-yl)methoxy]-indan-1-one | HCID 68989306 | — |
반응 단계
A solution of 5-hydroxyindanone (80 mg) and methanesulfonic acid (R)-1-(tetrahydrofuran-2-yl)methyl ester (107 mg) in DMF (1 mL) was stirred at 70° C. for 16 h. After adding water it was extracted with ether, dried over magnesium sulfate and concentrated. The residue was chromatographed on silica gel. In this way the product was obtained with molecular weight 232.28 (C14H16O3); MS (ESI): 233 (M+H+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08822495B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-7f3e6357e7c0499d9f9a3072dd89921e |
| 출처 메모 | uspto-grants-2014_09 |