1,2-Difluoro-4-nitrobenzene → HCID 68992896, 화합물

반응식

F[C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-])=O)=[CH:4][C:3]=1[F:11].[C:12]([O:16][C:17]([N:19]1[CH2:22][C:21]2([CH2:26][CH2:25][NH:24][CH2:23]2)[CH2:20]1)=[O:18])([CH3:15])([CH3:14])[CH3:13]>>[C:12]([O:16][C:17]([N:19]1[CH2:22][C:21]2([CH2:26][CH2:25][N:24]([C:2]3[CH:7]=[CH:6][C:5]([NH2:8])=[CH:4][C:3]=3[F:11])[CH2:23]2)[CH2:20]1)=[O:18])([CH3:15])([CH3:13])[CH3:14]

참가 물질

반응물 2

HCID 1230531,2-Difluoro-4-nitrobenzene

HCID 49757941Tert-butyl 2,6-diazaspiro[3.4]octane-2-carboxylate

생성물 1

HCID 68992896HCID 68992896, 화합물

실험 절차

According to methods E and F, 1,2-Difluoro-4-nitro-benzene was reacted with 2,6-Diaza-spiro[3.4]octane-2-carboxylic acid tert-butyl ester and hydrogenated. The product with the molecular weight of 321, 40 (C17H24FN3O2) was obtained in this way; MS (ESI): 322 (M+H+).

후처리

customThe product with the molecular weight of 321, 40 (C17H24FN3O2) was obtained in this way

출처 및 근거

ORD 기록: ord-662bcf1fb3a94ce68eb275bfad8b7632
출처 데이터셋: uspto-grants-2014_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08822495B2

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