Acetonitrile → 4-[2-(4-Fluorophenyl)-7-piperidin-4-ylimidazo-[1,2-a]pyridin-3-yl]piperidin-2-ylamine

반응식

[CH3:40][C:41]#[N:42].[NH2:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:33]3[cH:34][cH:35][c:36]([F:39])[cH:37][cH:38]3)[n:10][c:11]3[n:12]2[cH:13][cH:14][c:15]([CH:17]2[CH2:18][CH2:19][N:20]([C:23]([O:24][CH2:25][c:26]4[cH:27][cH:28][cH:29][cH:30][cH:31]4)=[O:32])[CH2:21][CH2:22]2)[cH:16]3)[n:7]1>>[NH2:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:33]3[cH:34][cH:35][c:36]([F:39])[cH:37][cH:38]3)[n:10][c:11]3[n:12]2[cH:13][cH:14][c:15]([CH:17]2[CH2:18][CH2:19][NH:20][CH2:21][CH2:22]2)[cH:16]3)[n:7]1

참가 물질

반응물 2

HCID 6342Acetonitrile

HCID 69055315Benzyl 4-[3-(2-aminopyrimidin-4-yl)-2-(4-fluorophenyl)imidazo[1,2-a]pyridin-7-yl]piperidine-1-carboxylate

생성물 1

HCID 248874184-[2-(4-Fluorophenyl)-7-piperidin-4-ylimidazo-[1,2-a]pyridin-3-yl]piperidin-2-ylamine

출처 및 근거

ORD 기록: ord-5a558535fa7b42849cc18e6c7ae835b9
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…