Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diisopropylethylamine → (S)-tert-butyl (1-(3-nitropyridin-4-yl)piperidin-3-yl)carbamate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diisopropylethylamine | HCID 81531 | — |
| 반응물 | tert-butyl N-[(3S)-piperidin-3-yl]carbamate | HCID 1514171 | — |
| 반응물 | 4-Chloro-3-nitropyridine | HCID 2735781 | — |
| 생성물 | (S)-tert-butyl (1-(3-nitropyridin-4-yl)piperidin-3-yl)carbamate | HCID 67499955 | 99% |
반응 단계
The method of Example 1 was followed using 1 eq each of 4-chloro-3-nitropyridine, (S)-3-N-Boc-amino piperidine and diisopropylethylamine yielding (S)-tert-butyl 1-(3-nitropyridin-4-yl)piperidin-3-ylcarbamate, (99%). LCMS (m/z): 323.1 (MH+); LC Rt=2.13 min.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08822497B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-946709c13b79443e96be0c40a098331a |
| 출처 메모 | uspto-grants-2014_09 |