Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Chloro-3-nitrobenzophenone → Tert-butyl 1-(4-benzoyl-2-nitro phenyl)piperidin-3-ylcarbamate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Chloro-3-nitrobenzophenone | HCID 41743 | — |
| 반응물 | 3-(Boc-amino)piperidine | HCID 4233041 | — |
| 용매 | N-methyl-2-pyrrolidone | HCID 13387 | — |
| 생성물 | Tert-butyl 1-(4-benzoyl-2-nitro phenyl)piperidin-3-ylcarbamate | HCID 69044915 | 90% |
반응 단계
Method 1 was followed using 4-chloro-3-nitrobenzophenone (1.0 eq), 3-(N-Boc-amino) piperidine (1.1 eq), and TEA (2.0 eq) in NMP yielding tert-butyl 1-(4-benzoyl-2-nitro phenyl)piperidin-3-ylcarbamate (90%). LCMS (m/z): 426.2 (MH+); LC Rt=3.49 min.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08822497B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-773c07133921440b9ace2ed353f1ff30 |
| 출처 메모 | uspto-grants-2014_09 |