8-Amino-5,5-dimethyl-1,3,4,5-tetrahydro-benzo[b]azepin-2-one → 2-[5-Chloro-2-(5,5-dimethyl-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-8-ylamino)-pyrimidin-4-ylamino]-N-ethyl-3-fluoro-benzamide
반응식
[Cl:16][c:17]1[n:18][cH:19][c:20]([Cl:36])[c:21]([NH:23][c:24]2[c:25]([C:26](=[O:27])[NH:28][CH2:29][CH3:30])[cH:31][cH:32][cH:33][c:34]2[F:35])[n:22]1.[NH2:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:15]1)[NH:7][C:8](=[O:14])[CH2:9][CH2:10][C:11]2([CH3:12])[CH3:13]>>[NH:1]([c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:15]1)[NH:7][C:8](=[O:14])[CH2:9][CH2:10][C:11]2([CH3:12])[CH3:13])[c:17]1[n:18][cH:19][c:20]([Cl:36])[c:21]([NH:23][c:24]2[c:25]([C:26](=[O:27])[NH:28][CH2:29][CH3:30])[cH:31][cH:32][cH:33][c:34]2[F:35])[n:22]1참가 물질
3
반응물 2
생성물 1
출처 및 근거
- ORD 기록
- ord-eb34c2572c4149d3bffeb054e9eb7080
- 출처 데이터셋
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
반응 노트
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