Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(3-Carbamoylphenyl)boronic acid → 4'-(1,3-Dioxolan-2-yl)-3'-(trifluoromethyl)-3-biphenylcarboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (3-Carbamoylphenyl)boronic acid | HCID 2737814 | — |
| 반응물 | 2-[4-Iodo-2-(trifluoromethyl)phenyl]-1,3-dioxolane | HCID 58276681 | — |
| 용매 | Toluene ethanol | HCID 21863594 | — |
| 생성물 | 4'-(1,3-Dioxolan-2-yl)-3'-(trifluoromethyl)-3-biphenylcarboxamide | HCID 67159994 | — |
반응 단계
The title compound was prepared from 3-(aminocarbonyl)phenyl boronic acid and 2-[4-iodo-2-(trifluoromethyl)phenyl]-1,3-dioxolane (I-IX-7) according to the procedure described for IX-10, using PhMe/EtOH (4:1) as organic cosolvents. Colorless solid. LC/MS (method A) 2.38 min; m/z 338 (M+H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08822518B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-46ac662b190145d0b275375fff7109d3 |
| 출처 메모 | uspto-grants-2014_09 |