1-Octanol → Benzene, 1,3-bis(1-phenylethenyl)-

HRID 703313

반응식

HRID 703313 반응식
[C:1]1([Mg]Cl)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:9]([C:12]1[CH:17]=[CH:16][CH:15]=[C:14](C(=O)C)[CH:13]=1)(=O)[CH3:10].[CH2:21](O)[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28]>O1CCCC1>[C:1]1([C:22]([C:23]2[CH:28]=[CH:27][CH:26]=[C:25]([C:9]([C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)=[CH2:10])[CH:24]=2)=[CH2:21])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

참가 물질

5

반응물 3

HCID 9571-OctanolHCID 232291,3-DiacetylbenzeneHCID 178478979HCID 178478979, 화합물

생성물 1

HCID 118622Benzene, 1,3-bis(1-phenylethenyl)-수율 95%

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

A Grignard reaction mixture was prepared by contacting 100 mL of 2M phenylmagnesium chloride in tetrahydrofuran with 0.1 mole m-diacetyl benzene. 100 mL of n-octanol were added to the Grignard reaction mixture. The tetrahydrofuran was removed by distillation during which the pot temperature rose to 175° C. in 2 hours. Gas chromatograph analysis showed that the alcohol had been dehydrated to m-bis-(1-phenylethenyl) benzene. Product yield was about 95%

후처리

  1. customA Grignard reaction mixture
  2. customwas prepared
  3. customThe tetrahydrofuran was removed by distillation during which the pot temperature

출처 및 근거

ORD 기록
ord-16fae7b23a8546628048023aa76092ba
출처 데이터셋
uspto-grants-1991_01
특허 번호
US04982029

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