Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dichloromethane → 3-(2,2,3,3,3-Pentafluoropropoxy)methyl-4-methyl-1-nitrobenzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dichloromethane | HCID 6344 | — |
| 반응물 | 2,2,3,3,3-Pentafluoropropanol | HCID 9872 | — |
| 반응물 | Potassium Hydroxide | HCID 14797 | — |
| 반응물 | 2-(Chloromethyl)-1-methyl-4-nitrobenzene | HCID 187952 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 3-(2,2,3,3,3-Pentafluoropropoxy)methyl-4-methyl-1-nitrobenzene | HCID 15070168 | — |
반응 단계
In 16.5 ml of dimethylformamide, 5.00 g (0.027 mol) of 2-methyl-5-nitrobenzyl chloride and 21.3 g (0.135 mol) of 2,2,3,3,3-pentafluoropropanol were dissolved. The solution was then added with 2.29 g (0.041 mol) of KOH pellets and stirred overnight. Dichloromethane was added and the precipitated salts were filtered out. The filtrate was acidified with dilute hydrochloric acid and then the solvents were distilled off.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04983209 |
| 출처 데이터셋 | uspto-grants-1991_01 |
| ORD ID | ord-fe6198eb9b0a45a8ba52b72219df5ea0 |
| 출처 메모 | uspto-grants-1991_01 |