5-Chloro-2-(methylthio)aniline → N-[5-chloro-2-(methylthio)phenyl]-1-benzofuran-2-sulfonamide

HRID 70344

반응식

HRID 70344 반응식
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([S:9][CH3:10])=[C:6]([CH:8]=1)[NH2:7].[O:11]1[C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=2[CH:13]=[C:12]1[S:20](Cl)(=[O:22])=[O:21]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([S:9][CH3:10])=[C:6]([NH:7][S:20]([C:12]2[O:11][C:15]3[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=3[CH:13]=2)(=[O:21])=[O:22])[CH:8]=1

참가 물질

3

반응물 2

HCID 27945775-Chloro-2-(methylthio)anilineHCID 27951721-Benzofuran-2-sulfonyl chloride

생성물 1

HCID 57378529N-[5-chloro-2-(methylthio)phenyl]-1-benzofuran-2-sulfonamide수율 60%

실험 절차

Following General Procedure B, the title compound (243 mg, 60%) was prepared from 5-chloro-2-(methylthio)aniline (CAS 16423-54-4) (200 mg, 1.15 mmol) and 1-benzofuran-2-sulfonyl chloride (249 mg, 1.152 mmol).

출처 및 근거

ORD 기록
ord-455fa9bb88b748b4b4a82f8ba2f64436
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08822530B2

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