Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → Tert-butyl (4-{[(2-amino-4-chlorophenyl)thio]methyl}-1,3-thiazol-2-yl)carbamate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 2-Amino-4-chlorobenzenethiol | HCID 12000 | — |
| 반응물 | tert-Butyl (4-(chloromethyl)thiazol-2-yl)carbamate | HCID 45117840 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | Tert-butyl (4-{[(2-amino-4-chlorophenyl)thio]methyl}-1,3-thiazol-2-yl)carbamate | HCID 86690989 | 100.7% |
반응 단계
Following General Procedure A, the title compound (588 mg, 67%) was prepared from 2-amino-4-chlorobenzenethiol (376 mg, 2.36 mmol), tert-butyl [4-(chloromethyl)-1,3-thiazol-2-yl]carbamate (391 mg, 1.57 mmol) and K2CO3 (1.08 g, 3.45 mmol) in DMF (10 ml).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08822530B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-6d236cee94ec4db79cef9e22294230fe |
| 출처 메모 | uspto-grants-2014_09 |