Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Acid → 3-((2-amino-4-chlorophenyl)thio)-N,N-dimethylpropanamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Acid | HCID 176 | — |
| 반응물 | 2-Amino-4-chlorobenzenethiol | HCID 12000 | — |
| 반응물 | N,N-Dimethylacrylamide | HCID 17587 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 3-((2-amino-4-chlorophenyl)thio)-N,N-dimethylpropanamide | HCID 60961870 | 83% |
반응 단계
The solution of 2-amino-4-chlorobenzenethiol (824 mg, 5.126 mmol), N,N-dimethylacrylamide (512 mg, 5.162 mmol), and HOAc (1 ml) in CH2Cl2 (10 ml) was stirred at room temperature for 4 days. The solvent was removed and the residue was loaded on silica column and purified to yield a white solid (1.08 g, 83%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08822530B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-d56a93cafd944ebe8d2c4ac166229472 |
| 출처 메모 | uspto-grants-2014_09 |