Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,4-Difluorobenzenesulfonyl Chloride → 3-[(4-chloro-2-{[(2,4-difluorophenyl)sulfonyl]amino}phenyl)thio]-N,N-dimethylpropanamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,4-Difluorobenzenesulfonyl Chloride | HCID 2734273 | — |
| 반응물 | 3-((2-amino-4-chlorophenyl)thio)-N,N-dimethylpropanamide | HCID 60961870 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 생성물 | 3-[(4-chloro-2-{[(2,4-difluorophenyl)sulfonyl]amino}phenyl)thio]-N,N-dimethylpropanamide | HCID 67971905 | 72% |
반응 단계
Following General Procedure B, the title compound (364 mg, 72%) was prepared from 3-((2-amino-4-chlorophenyl)thio)-N,N-dimethylpropanamide (300 mg, 1.167 mmol) and 2,4-difluorobenzene-1-sulfonyl chloride (248 mg, 1.167 mmol) in pyridine (5 ml).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08822530B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-30123de4357b44b796764f38e4f8299a |
| 출처 메모 | uspto-grants-2014_09 |