1-Benzofuran-2-sulfonyl chloride → N-{5-chloro-2-[(2-pyridin-2-ylethyl)thio]phenyl}-1-benzofuran-2-sulfonamide

HRID 70369노트

반응식

HRID 70369 반응식
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([S:9][CH2:10][CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][N:13]=2)=[C:6]([CH:8]=1)[NH2:7].[O:18]1[C:22]2[CH:23]=[CH:24][CH:25]=[CH:26][C:21]=2[CH:20]=[C:19]1[S:27](Cl)(=[O:29])=[O:28]>N1C=CC=CC=1>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([S:9][CH2:10][CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][N:13]=2)=[C:6]([NH:7][S:27]([C:19]2[O:18][C:22]3[CH:23]=[CH:24][CH:25]=[CH:26][C:21]=3[CH:20]=2)(=[O:28])=[O:29])[CH:8]=1

참가 물질

4

반응물 2

HCID 27951721-Benzofuran-2-sulfonyl chlorideHCID 608905105-Chloro-2-((2-(pyridin-2-yl)ethyl)thio)aniline

생성물 1

HCID 67972452N-{5-chloro-2-[(2-pyridin-2-ylethyl)thio]phenyl}-1-benzofuran-2-sulfonamide

시약·촉매·용매 1

HCID 1049Pyridine용매

실험 절차

Following General Procedure B, the title compound was prepared from 5-chloro-2-((2-(pyridin-2-yl)ethyl)thio)aniline (439 mg, 1.663 mmol) and benzofuran-2-sulfonyl chloride (2×359 mg, 2×1.663 mmol) in pyridine (5 ml).

출처 및 근거

ORD 기록
ord-93aadee128e04763b8e2963a3320a8ad
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08822530B2

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