Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triphenylphosphine → 2-((2-(1H-pyrazol-4-yl)ethyl)thio)-5-chloroaniline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triphenylphosphine | HCID 11776 | — |
| 반응물 | 2-Amino-4-chlorobenzenethiol | HCID 12000 | — |
| 반응물 | 2-(1H-Pyrazol-4-yl)ethanol | HCID 4293604 | — |
| 반응물 | Di-tert-butyl diazene-1,2-dicarboxylate | HCID 6034084 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 2-((2-(1H-pyrazol-4-yl)ethyl)thio)-5-chloroaniline | HCID 67972877 | — |
반응 단계
Following the General Procedure J, the title intermediate was prepared from 2-(1H-pyrazol-4-yl) ethanol (472 mg, 4.218 mmol), 2-amino-4-chlorobenzenethiol (1.01 g, 6.327 mmol), PPh3 (2.21 g, 8.436 mmol) and di-tert-butylazodicarboxylate (1.9 g, 8.436 mmol) in CH2Cl2 (20 ml).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08822530B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-c8886a7c84de41818cd19b52db18dc58 |
| 출처 메모 | uspto-grants-2014_09 |