참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Dimethylformamide | HCID 6228 | — |
| 반응물 | Isobutyl acrylate | HCID 7819 | — |
| 반응물 | Potassium Hydroxide | HCID 14797 | — |
| 반응물 | 5-Benzylidenehydantoin | HCID 97857 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | Isobutyl 4-benzylidene-2,5-dioxo-1-imidazolidinepropionate | HCID 54303283 | 81.1% |
반응 단계
20 g (0.106 mol) of benzalhydantoin, 14.9 g (0.117 mol) of isobutyl acrylate and 1.2 g (0.02 mol) of potassium hydroxide were added to 150 ml of DMF, and the mixture was stirred at 110° C. for 2 hours. After cooling, the reaction solution was added with 300 ml of toluene and crystallized. The crystals were filtered out and dried to obtain 27.2 g of isobutyl 4-benzylidene-2,5-dioxo-1-imidazolidinepropionate (yield: 81%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04985237 |
|---|
| 출처 데이터셋 | uspto-grants-1991_01 |
|---|
| ORD ID | ord-9c4b640ab09847aca411b2a15f5e8fee |
|---|
| 출처 메모 | uspto-grants-1991_01 |
|---|
