2-Amino-4-chlorobenzenethiol → N-{2-[(3-aminobenzyl)thio]-5-chlorophenyl}-2,4-difluorobenzenesulfonamide

HRID 70402

반응식

HRID 70402 반응식
[NH2:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[SH:9].Br[CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[C:14]([N+:18]([O-])=O)[CH:13]=1.[F:21][C:22]1[CH:27]=[C:26]([F:28])[CH:25]=[CH:24][C:23]=1[S:29](Cl)(=[O:31])=[O:30]>>[NH2:18][C:14]1[CH:13]=[C:12]([CH:17]=[CH:16][CH:15]=1)[CH2:11][S:9][C:3]1[CH:4]=[CH:5][C:6]([Cl:8])=[CH:7][C:2]=1[NH:1][S:29]([C:23]1[CH:24]=[CH:25][C:26]([F:28])=[CH:27][C:22]=1[F:21])(=[O:31])=[O:30]

참가 물질

4

반응물 3

HCID 120002-Amino-4-chlorobenzenethiolHCID 77568Benzene, 1-(bromomethyl)-3-nitro-HCID 27342732,4-Difluorobenzenesulfonyl Chloride

생성물 1

HCID 57378104N-{2-[(3-aminobenzyl)thio]-5-chlorophenyl}-2,4-difluorobenzenesulfonamide

실험 절차

Following General Procedure A, B, and K, the title compound was prepared from 2-amino-4-chloro-benzenethiol, 1-bromomethyl-3-nitro-benzene, and 2,4-difluoro-benzenesulfonyl chloride.

출처 및 근거

ORD 기록
ord-e5e3350ac55e436aaf3f8db7a9f1ac12
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08822530B2

연결된 노트

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