Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-(3-Aminopropyl)morpholine → N-[3-(4-Morpholinyl)propyl]-4-methylpyridazino[4,5-b]indolizin-1-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-(3-Aminopropyl)morpholine | HCID 61055 | — |
| 반응물 | 1-Chloro-4-methylpyridazino[4,5-b]indolizine | HCID 15713312 | — |
| 생성물 | N-[3-(4-Morpholinyl)propyl]-4-methylpyridazino[4,5-b]indolizin-1-amine | HCID 15713316 | — |
반응 단계
Following the procedure of Example 1, reaction of one equivalent of 1-chloro-4-methylpyridazino[4,5-b]indolizine and 10 equivalents of 4-(3-aminopropyl)morpholine gave the title compound as the free base which was converted to the dihydrochloride salt, mp. 295°-296° C. (after recrystallization from ethanol).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04985560 |
| 출처 데이터셋 | uspto-grants-1991_01 |
| ORD ID | ord-a6000ef64477480795ef1f47757fc758 |
| 출처 메모 | uspto-grants-1991_01 |