Acetic Acid → Flumiclorac-pentyl

HRID 704094

반응식

HRID 704094 반응식
[Cl:1][C:2]1[C:8]([O:9][CH2:10][C:11]([O:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18])=[O:12])=[CH:7][C:5]([NH2:6])=[C:4]([F:19])[CH:3]=1.[C:20]([OH:23])(=O)[CH3:21]>O>[Cl:1][C:2]1[C:8]([O:9][CH2:10][C:11]([O:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18])=[O:12])=[CH:7][C:5]([N:6]2[C:20](=[O:23])[C:21]3[CH2:2][CH2:3][CH2:4][CH2:5][C:7]=3[C:8]2=[O:9])=[C:4]([F:19])[CH:3]=1

참가 물질

4

반응물 2

HCID 176Acetic AcidHCID 146178504-Chloro-2-fluoro-5-(pentyloxycarbonylmethyloxy)aniline

생성물 1

HCID 443048Flumiclorac-pentyl수율 178.9%

시약·촉매·용매 1

HCID 962Water용매

실험 절차

A mixture of the compound (II) (12.0 g), 3,4,5,6-tetarhydrophthalic anhydride (7.56 g) and acetic acid (50 g) was heated at 90° to 95° C. for 7 hours. The reaction mixture was cooled to room temperature, and water (75 g) was added thereto. The precipitated crystals were collected by filtration to give the compound (I) (15.7 g).

후처리

  1. temperaturewas heated at 90° to 95° C. for 7 hours
  2. filtrationThe precipitated crystals were collected by filtration

출처 및 근거

ORD 기록
ord-dad9a81e8d284b75bba1c856f5f89f74
출처 데이터셋
uspto-grants-1991_01
특허 번호
US04985570

연결된 노트

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