Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetophenone, 2',4'-dichloro-5'-fluoro- → 2,4-Dichloro-5-fluorobenzoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetophenone, 2',4'-dichloro-5'-fluoro- | HCID 727250 | — |
| 반응물 | HCID 178527019 | HCID 178527019 | — |
| 생성물 | 2,4-Dichloro-5-fluorobenzoic acid | HCID 688138 | — |
반응 단계
Namely, 2,4-dichloro-5-fluoroacetophenone is subjected to a haloform reaction in a 12% sodium hypophosphite aqueous solution to obtain 2,4-dichloro-5-fluorobenzoic acid. Then, this benzoic acid is reacted with an alcohol or with a phenol in the presence of an acid catalyst to obtain the above-mentioned fluorine-containing benzoate.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04985588 |
| 출처 데이터셋 | uspto-grants-1991_01 |
| ORD ID | ord-aecb18ae08a242f6b4dacf28a42ba04f |
| 출처 메모 | uspto-grants-1991_01 |