2-Amino-4-chlorobenzenethiol → N-(5-chloro-2-{[3-(dimethylamino)propyl]thio}phenyl)-1-benzofuran-2-sulfonamide

HRID 70421

반응식

HRID 70421 반응식
[NH2:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[SH:9].Cl.Cl[CH2:12][CH2:13][CH2:14][N:15]([CH3:17])[CH3:16].[O:18]1[C:22]2[CH:23]=[CH:24][CH:25]=[CH:26][C:21]=2[CH:20]=[C:19]1[S:27](Cl)(=[O:29])=[O:28]>>[Cl:8][C:6]1[CH:5]=[CH:4][C:3]([S:9][CH2:12][CH2:13][CH2:14][N:15]([CH3:17])[CH3:16])=[C:2]([NH:1][S:27]([C:19]2[O:18][C:22]3[CH:23]=[CH:24][CH:25]=[CH:26][C:21]=3[CH:20]=2)(=[O:28])=[O:29])[CH:7]=1

참가 물질

4

반응물 3

HCID 120002-Amino-4-chlorobenzenethiolHCID 943083-(Dimethylamino)propyl chloride hydrochlorideHCID 27951721-Benzofuran-2-sulfonyl chloride

생성물 1

HCID 67972245N-(5-chloro-2-{[3-(dimethylamino)propyl]thio}phenyl)-1-benzofuran-2-sulfonamide

실험 절차

Following General Procedure A, B, the title compound was prepared from 2-Amino-4-chloro-benzenethiol, (3-chloro-propyl)-dimethyl-amine hydrochloride and 1-benzofuran-2-sulfonyl chloride.

출처 및 근거

ORD 기록
ord-8328a27ea6f44d06a62e31affbdd206c
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08822530B2

연결된 노트

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