Ethyl 4-styrylpiperidine-1carboxylate → Ethyl 4-(2-phenylethyl)piperidine-1-carboxylate
반응식
[CH:1]([CH:9]1[CH2:14][CH2:13][N:12]([C:15]([O:17][CH2:18][CH3:19])=[O:16])[CH2:11][CH2:10]1)=[CH:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1>C(OCC)(=O)C.[Pd]>[C:3]1([CH2:2][CH2:1][CH:9]2[CH2:10][CH2:11][N:12]([C:15]([O:17][CH2:18][CH3:19])=[O:16])[CH2:13][CH2:14]2)[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1참가 물질
4
실험 절차
A mixture of 0.80 g of ethyl 4-styrylpiperidine-1carboxylate and 80 mg of 10% palladium-on-carbon in ethyl acetate (40 ml) was subjected to catalytic reduction at room temperature until stopping of hydrogen absorption. The catalyst was filtered off, and the filtrate was concentrated under reduced pressure to give 0.80 g of ethyl 4-(2-phenylethyl)piperidine-1-carboxylate.
후처리
- customwas subjected to catalytic reduction at room temperature
- customuntil stopping of hydrogen absorption
- filtrationThe catalyst was filtered off
- concentrationthe filtrate was concentrated under reduced pressure
출처 및 근거
- ORD 기록
- ord-72ab2d8da791486eb82bc898cecd4a57
- 출처 데이터셋
- uspto-grants-1991_01
- 특허 번호
- US04987132
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