4-Methoxy cinnamic acid → 3-(p-Methoxyphenyl)propionic acid

HRID 704396노트

반응식

HRID 704396 반응식
[CH3:1][O:2][C:3]1[CH:13]=[CH:12][C:6]([CH:7]=[CH:8][C:9]([OH:11])=[O:10])=[CH:5][CH:4]=1.[H][H]>CO.[Pd]>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([CH2:7][CH2:8][C:9]([OH:11])=[O:10])=[CH:12][CH:13]=1

참가 물질

5

반응물 2

HCID 132454-Methoxy cinnamic acidHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 957503-(p-Methoxyphenyl)propionic acid수율 100.5%

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 887Methanol용매

실험 절차

10% Palladium-on-carbon (200 mg) was added to a solution of 5.34 g of 4-methoxycinnamic acid in methanol, and the mixture was stirred under hydrogen until hydrogen gas absorption ceased. The catalyst was filtered off, and the filtrate was concentrated under reduced pressure to give 5.43 g of 3-(4-methoxyphenyl)propionic acid.

후처리

  1. filtrationThe catalyst was filtered off
  2. concentrationthe filtrate was concentrated under reduced pressure

출처 및 근거

ORD 기록
ord-267d2b1845324df4bb8b26e892935043
출처 데이터셋
uspto-grants-1991_01
특허 번호
US04987132

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