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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 704446생성일: 2026년 10월 26일

1-(3-Methyl-3-phenylbutyl)-4-[2-(3-pyridyl)thiazolidin-4-ylcarbonyl]piperazine → YM 264

https://huagongshe.com/reaction/704446

반응식

참여 물질

역할이름HCID투입량
반응물1-(3-Methyl-3-phenylbutyl)-4-[2-(3-pyridyl)thiazolidin-4-ylcarbonyl]piperazineHCID 131436—
반응물Fumaric AcidHCID 444972—
용매EthanolHCID 702—
생성물YM 264HCID 643932272.5%

반응 단계

To a solution of 1-(3-methyl-3-phenylbutyl)-4[2-(3-pyridyl)thiazolidin-4-ylcarbonyl]piperazine (1.22 g) in ethanol (6 ml) was added fumaric acid (0.32 g) and the mixture was dissolved. The solution was stirred at room temperature for 2 hours and allowed to stand at room temperature for a day. The resultant crystals were collected by filtration, washed with ethanol and then dried to give 1.08 g of 1-(3-methyl-3-phenylbutyl]-4-[2-(3-pyridyl)thiazolidin-4-ylcarbonyl]piperazine fumarate.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US04987132
출처 데이터셋uspto-grants-1991_01
ORD IDord-88b7f8b58e1348cf9f62240b69c336cd
출처 메모uspto-grants-1991_01