Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Fluoropiperidine hydrochloride → 5-Butyl-N-(2,4-dimethoxybenzyl)-3-(5-(4-fluoropiperidin-1-yl)pentyl)-1H-pyrazolo[4,3-d]pyrimidin-7-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Fluoropiperidine hydrochloride | HCID 2759158 | — |
| 반응물 | 5-Butyl-3-(5-chloropent-1-yn-1-yl)-N-(2,4-dimethoxybenzyl)-1H-Pyrazolo[4,3-d]pyrimidin-7-amine | HCID 178441810 | — |
| 반응물 | (5)-5-Butyl-N-(2,4-dimethoxybenzyl)-3-(5-(3-fluoropyrrolidin-1-yl)pentyl)-1H-pyrazolo[4,3-d]pyrimidin-7-amine | HCID 178441816 | — |
| 생성물 | 5-Butyl-N-(2,4-dimethoxybenzyl)-3-(5-(4-fluoropiperidin-1-yl)pentyl)-1H-pyrazolo[4,3-d]pyrimidin-7-amine | HCID 178441814 | — |
반응 단계
Prepared similarly to Intermediate 25 from and 5-butyl-3-(5-chloropent-1-yn-1-yl)-N (2,4-dimethoxybenzyl)-1H-pyrazolo[4,3-d]pyrimidin-7-amine and 4-fluoropiperidine hydrochloride
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09173872B2 |
| 출처 데이터셋 | uspto-grants-2015_11 |
| ORD ID | ord-4fa57fafee0f4f20b7aec840fdeaceb0 |
| 출처 메모 | uspto-grants-2015_11 |