Sulfuric Acid → 4-Amino-2-chlorobenzenesulfonic acid

HRID 705460

반응식

HRID 705460 반응식
[Cl:1][C:2]1[CH:3]=[C:4]([CH:6]=[CH:7][CH:8]=1)[NH2:5].[S:9](=O)(=[O:12])([OH:11])[OH:10]>O>[NH2:5][C:4]1[CH:6]=[CH:7][C:8]([S:9]([OH:12])(=[O:11])=[O:10])=[C:2]([Cl:1])[CH:3]=1

참가 물질

4

반응물 2

HCID 1118Sulfuric AcidHCID 79323-Chloroaniline

생성물 1

HCID 158503594-Amino-2-chlorobenzenesulfonic acid

시약·촉매·용매 1

HCID 962Water용매

실험 절차

0.4 mL of 3-chloroaniline was slowly added to 4 mL of a fuming sulfuric acid and stirred at room temperature overnight. Cooling it down to 0° C., the reaction solution was poured in water, and a precipitated solid substance was taken by filtration. The solid substance was dissolved in an aqueous solution of 2N sodium hydroxide. Then, a concentrated hydrochloric acid wad added thereto to make the liquid acidic. The precipitated solid substance was filtered out to obtain a crude product of 4-amino-2-chlorobenzenesulfonic acid.

후처리

  1. temperatureCooling it down to 0° C.
  2. filtrationa precipitated solid substance was taken by filtration
  3. dissolutionThe solid substance was dissolved in an aqueous solution of 2N sodium hydroxide
  4. additionThen, a concentrated hydrochloric acid wad added
  5. filtrationThe precipitated solid substance was filtered out

출처 및 근거

ORD 기록
ord-05c6268ef4854e0c8fdca05e961230fe
출처 데이터셋
uspto-grants-2015_11
특허 번호
US09174932B2

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